Apalutamide-PRODUCT-CHENGHUI PHARMACEUTICAL GROUP LTD

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Product description

Product name: Apalutamide

English Synonyms: ARN-509; 4-(7-(6-cyano-5-(trifluoroMethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspirooctan-5-yl)-2-fluoro-N-MethylbenzaMide; ARN509; Benzamide; Apalutamide; Apalutamide impurity AR509;Benzamide,4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-; 4-[7 -[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamideARN-509. AR509100G;4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide. ARV-509

CAS No.: 956104-40-8

Molecular Formula: C21H15F4N5O2S

Molecular weight: 477.43

EINECS No.: 807-449-9

Properties: white powder

Density: 1.59±0.1g/cm3(Predicted)

Storage condition: Storeat-20°C

Solubility: ≥23.85mChemicalbookg/mL in DMSO; insoluble in water; ≥7.33mg/mL in ethanol

Form: solid

Acidity coefficient: (pKa)13.83±0.46(Predicted)

Use: Used as pharmaceutical intermediates for anti-ED drugs.

Product specification: 1kg/barrel, 2kg/barrel, 5kg/barrel, 10kg/barrel, 15kg/barrel, 20kg/barrel, 25kg/barrel, etc., and can be separately subcontracted according to customers' requirements.

Price: Price is for reference only, call us for one-to-one quotation.

Apalutamide Upstream and downstream product information

Upstream raw material: 5-isothiocyanoyl-3-(trifluoromethyl)pyridine-2-cyano 4-[(1-cyanocyclobutyl)amino]-N-methylbenzamide

Advantageous products

Chenghui Pharmaceutical: Vonorazan fumarate and intermediates, dagliflozin and intermediates, clidinaforol and intermediates, letemovir and intermediates, mirtazapine, veterinary products (intermediates of floretanol, aflatanol and sarolanol and other intermediates), loperamide hydrochloride and intermediates, local anesthesia series (lidocaine, lidocaine, proparacaine, proparacaine, bupivacaine hydrochloride, etc.), etc., which cover local anesthesia, antiviral drugs and other drugs. Our products cover the fields of local anesthesia, anti-virus, cardio-cerebral vascular system, anti-tumor, gastrointestinal tract, diabetes, veterinary medicine and so on. Our main advantages are high quality products, reasonable price, fast delivery and considerate after-sales service, and we support customized products.

Molecular structure：